The brain on fire - Run4Brain – support brain research

Multiple sclerosis (MS) is a chronic neurological disorder of the central nervous system. This disease affects 1 in 1000 people in Belgium, and approximately 2.8 million people worldwide. It is characterized by inflammatory lesions in the brain and spinal cord, in which myelin, the protective layer around nerve fibers, is damaged. This damage disrupts communication between the brain and the rest of the body, leading to a wide range of symptoms. These symptoms can vary from fatigue, muscle weakness, and coordination problems to issues with vision, speech, and cognitive function. MS is an unpredictable disease, with symptoms occurring in episodes of flare-ups and remissions, or otherwise slow progression. While there is currently no cure for MS, there are treatments available that can alleviate symptoms, reduce flare-ups, and slow the progression of the disease.

At the 4brain lab research is conducted on the underlying mechanisms in MS. We investigate which cells are involved in inflammation and how myelin repair can be influenced. Among other things, research is being conducted to determine if nerve stimulation of the vagus nerve can reduce inflammation in MS and improve recovery. Furthermore, clinical research is also being conducted on how MS patients can be best supported, for example investigating the advantages of specialized MS nurses in MS care. We also investigate the cerebrospinal fluid and electrical nerve responses of patients that may predict the MS disease course, in order to optimize treatment based on individual patient characteristics.

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